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TERMIS-AM 2025 Detailed Scientific Program
 
Legend: Plenary Sessions SYIS Activities Society Meetings

Scientific Concurrent Sessions

 Workshops Social Events
4:00 PM – 4:15 PM Transition break
4:15 PM – 4:45 PM TERMIS General Assembly
4:45 PM – 5:00 PM Transition break
5:00 PM – 5:15 PM TERMIS-AM Chair Welcome
5:15 PM – 5:30 PM Welcome From the TERMIS-AM 2025 Conference Co-Chairs
5:30 PM – 6:30 PM

Opening Plenary Symposium

Biomanufacturing: Moving Your Ideas from an Academic Lab Towards the Clinic, Dean Kamen & Building the Industrial Base for Human Cell and Tissue Manufacturing, Tom Bollenbach

6:30 PM – 8:30 PM Welcome Reception &
Poster Session 1 & Exhibitor Viewing
(Location: Exhibition Area – Level 3)
1:00 PM – 3:00 PM TERMIS-AM Council Meeting
1:00 PM – 4:00 PM Pre-Conference Workshop:
Artificial Intelligence (AI) in Biofabrication, Tissue Engineering, and Regenerative Medicine: From Experimental Design and Advanced Analyses Towards Enabling Therapeutic Applications
(*registration required)
1:00 PM – 4:00 PM Pre-Conference Workshop:
Innovation and Navigating FDA Regulatory Pathways in Tissue Engineering
(*registration required)
1:00 PM – 4:00 PM Pre-Conference Workshop:
What Now? Commercial Translation and Entrepreneurship in Regenerative Medicine
(*registration required)
8:00 AM – 9:30 AM Scientific Concurrent Sessions 1

Session 1:
Advanced Biofabrication Strategies for Cancer and Disease Modeling
Session Chairs: Rui L Reis, Luiz Bertassoni
8:00 AM – 8:30 AM Keynote Lecture: Precision Biofabrication of Complex Tumor Microenvironments with High Resolution and Spatial Organization, Luiz Bertassoni
8:30 AM – 8:45 AM OP-1 3D Biofabricated Multilayered Skin Models Recapturing Autoimmune Pathogenesis, Fanben Meng, US
8:45 AM – 9:00 AM OP-2 Three-Dimensional In Vitro Models of Cell-Cell Interactions in the Microenvironment of Early- and Late-Stage High-Grade Serous Ovarian Carcinoma, Kathleen Burkhard, US
9:00 AM – 9:15 AM OP-3 Biofabrication of Intestinal Barrier Matrix With Crypts/Villi Topography Using Sacrificial and Bioactive Hydrogels, Chien-Chi Lin, US
9:15 AM – 9:30 AM OP-4 Characterizing 3D PEG-Based Lung Tumor Model Using RNA Sequencing, Suzanne Lightsey, US
9:30 AM – 10:00 AM Coffee Break
10:00 AM – 12:00 PM

Plenary Speaker & Award Session 1

Transplant Immunology: Preventing Transplant Rejection, Xunrong Luo

2025 Jensen Tissue Engineering Award
Rocky S. Tuan

12:00 PM – 1:30 PM Lunch Break on Your Own
&
Empowering Next Leaders in TERM Luncheon (Greco Room) *registration required
1:30 PM – 3:00 PM Scientific Concurrent Sessions 2
Session 6:
Designing Hydrogel Biomaterials for Ocular Tissue Engineering
Session Chairs: Evelyn Yim, Muhammad Rizwan, Sophia Lu
1:30 PM – 1:50 PM Keynote Lecture: Engineering the Outer neural Retina, Budd Tucker
1:50 PM – 2:10 PM Keynote Lecture: Modular Hydrogels to Improve Ocular Cell Growth, Transplantation and Tissue Repair, Muhammad Rizwan
2:10 PM – 2:30 PM Keynote Lecture: Multifunctional Bandage Lens and Bioadhesive with Proteoglycan 4 (PRG4) for the Treatment of Corneal Wounds, Tannin Schmidt
2:30 PM – 2:45 PM OP-19 Survival and Integration of Human iPSC Derived Choroidal Endothelial Cells in a Rodent Model of Age-Related Macular Degeneration, Narendra Pandala, US
2:45 PM – 3:00 PM OP-20Multi-Step 3D Printed Platform for Systematically Studying the Role of Retinal Axon Guidance Cues, Jacob Schimelman, US
3:00 PM – 3:05 PM Transition Break
3:05 PM – 4:35 PM Scientific Concurrent Sessions 3
Session 11:
Business Plan Competition
Session Chairs: Paul Dalton
3:05 PM – 3:15 PM Pitch #1: Laetech, Brian Webb
3:15 PM – 3:25 PM Pitch #2: Linton Life Sciences, Julio Aleman, US
3:25 PM – 3:35 PM Pitch #3: Mitoway, Bin Jiang
3:35 PM – 3:45 PM Pitch #4: NovaGyn, Rebecca Thomson, US
3:45 PM – 3:55 PM Pitch #5: Organoro, Rosaria Santoro, Italy
3:55 PM – 4:20 PM Passion, Progress, and Perseverance: An Entrepreneurial Journey in Tissue Therapeutics, Adam Jakus, US
4:20 PM – 4:35 PM Business Plan Winner Announcements
4:35 PM – 5:05 PM Coffee Break
5:05 PM – 6:35 PM Scientific Concurrent Sessions 4

Session 16:
Advancing Women’s Health: Integrating Sex-Based Biology and Convergent Tissue Engineering
Session Chair: Joyce Wong, Ariella Shikanov
5:05 PM – 5:35 PM Keynote Lecture: Sex-Specific Mechanobiology and the Impact on Biomaterial Development, Josephine Allen
5:35 PM – 5:50 PM OP-57 Characterization of Sex-Based Differences in Integrin-Mediated Endothelialization on Bioactive PEGDA Hydrogels, Aashee Budhwani, US
5:50 PM – 6:05 PM OP-58 Sex Differences Between Two Major Macrophage Cell Lines in 2D and 3D Cultures Reveal Divergent Functional Responses to 17β-Estradiol (e2), Alison M Veintimilla, US
6:05 PM – 6:20 PM OP-59 Bioengineered Ovarian Constructs to Prevent Osteoporosis in Rat Model of Ovarian Hormone Loss, Vivek Prakash, US
6:20 PM – 6:35 PM OP-60 Development and Host Response Evaluation of a Polyurethane-Based Microfiber Mesh for Breast Reconstruction in a Rat Model, Laura Modica de Mohac, Italy
6:35 PM – 8:00 PM Poster Session 2 & Exhibitor Viewing / Reception
(Location: Exhibition Area – Level 3)
8:00 PM – 9:00 PM SYIS Networking Event
(Location: Exhibition Area – Level 3)
8:00 AM – 9:30 AM Scientific Concurrent Sessions 1

Session 2:
Biomimetic In Vitro Model Systems for Cardiovascular Engineering
Session Chairs: Chris Bashur, Clotilde Castaldo, Shumaim Barooj
8:00 AM – 8:15 AM OP- 5 Reconstructing Native Soluble Cues to Enhance Endothelial Cell Maturation In Bioengineered
Whole Lung Vascular Model, Yifan Yuan, US
8:15 AM – 8:30 AM OP-6 A Perfusable Leaf Model to Investigate Endothelialization of Engineered Constructs, Chris Bashur, US
8:30 AM – 8:45 AM OP-7 Nicotine and Extracellular Matrix Interactions on Endothelial-to-Mesenchymal Transition, Ngan Huang, US
8:45 AM – 9:00 AM OP-8 Mature Cardiac Cell Manufacturing for Cardiotoxicity Screening, Carlos Barreto Gamarra, US
9:00 AM – 9:15 AM OP-9 Replicating the Cell Population of the Developing Human Heart for Cardiac Grafts, Dominic Rütsche, US
9:15 AM – 9:30 AM OP-10 3D Bioprinted Microporous Collagen Scaffolds for Studying Physiological Platelet Activation and Clotting Factor Binding, Antonio Pereira Tavares, US
9:30 AM – 10:00 AM Coffee Break
12:00 PM – 1:30 PM Lunch Break on Your Own
&
Empowering Next Leaders in TERM Luncheon (Greco Room) *registration required
1:30 PM – 3:00 PM Scientific Concurrent Sessions 2

Session 7:
Engineering and Regeneration of Airway, Digestive, or Urogenital Systems
Session Chairs: Riccardo Gottardi, Harsha Ramaraju
1:30 PM – 1:45 PM OP-21 Drug-Eluting Hyaluronic Acid Microgels Reduce Upper Airway Fibrosis in a Rat Model of Vocal Fold Scarring, Riccardo Gottardi, US
1:45 PM – 2:00 PM OP-22 Mapping Disease-Specific Pulmonary Fibroblast Niches by Spatial Proteomics, Jason Guo, US
2:00 PM – 2:15 PM OP-23 Engineered Immunological Niches for Early Diagnosis of Lupus Nephritis,
Shivanie Kodikalla, Mahesh Kumar, US
2:15 PM – 2:30 PM RF-47 Coaxial PHB-SF Electrospun Scaffolds With Optimized Mechanical And Biological Properties For Pelvic Floor Reconstruction, Rebecca Thomson, US
2:30 PM – 2:45 PM OP-25 Whole Mouse Kidney Decellularization and Vascular Recellularization Using Human Stem Cells, Anupama Bhadwal, Canada
2:45 PM – 3:00 PM OP-26 Development of an In Vitro Lung Organ Tissue-Equivalent Platform Incorporating Primary Human Cells for the Assessment of Radiation Exposure and Radioprotectant Efficacy, Dariya Lizanets, US
3:00 PM – 3:05 PM Coffee Break
3:05 PM – 4:35 PM Scientific Concurrent Sessions 3

Session 12:
Engineering Transplantation Tolerance: A Key to Next-Generation Regenerative Medicine
Session Chairs: Maria Coronel, Jessica Weaver, Derek Hwang
3:05 PM – 3:35 PM Keynote Lecture: Tolerogenic Trophoblast Cell Therapy Limits Bystander Xenograft Rejection, Jessica Weaver
3:35 PM – 3:50 PM OP-41 Microfabricated Systems for In Situ Engineering Tolerogenic Dermal Microenvironments, Robert Oakes, US
3:50 PM – 4:05 PM OP-42 Engineered Immunological Niche Reveals Immune Signature Driving Islet Allograft Acceptance, Jyotirmoy Roy, US
4:05 PM – 4:20 PM OP-43 FasL-Microparticles for Long-Term Immune Protection of Neural Stem Cell Transplants in Spinal Cord Injury, Brooke Smiley, US
4:20 PM – 4:35 PM OP-44 Human Stem Cell-Derived Beta Cell Macroencapsulation Prevents Immune Rejection by Direct Antigen Recognition in a Humanized Mouse Model, Jinal Mehta, US
4:35 PM – 5:05 PM Coffee Break
5:05 PM – 6:35 PM Scientific Concurrent Sessions 4

Session 17:
Pathways to Innovation: Perspectives, Challenges, and Breakthroughs in Tissue Engineering and Regenerative Medicine
Session Chair: Karina Nakayama, Helen LU
5:05 PM – 5:35 PM Keynote Lecture: Making Space for Fat: Innovation Through Inclusion in Tissue Engineering, Evangelia Bellas
5:35 PM – 6:05 PM Keynote Lecture: Autonomous RUNX2 Suppression in Engineered Cartilage, Rhima Coleman
6:05 PM – 6:35 PM Keynote Lecture: Human Stem Cell-Based Articular Tissue Engineering: From Joint Regeneration to Joint-on-a-Chip (miniJoint), Rocky Tuan
6:35 PM – 8:00 PM Poster Session 2 & Exhibitor Viewing / Reception
(Location: Exhibition Area – Level 3)
8:00 PM – 9:00 PM SYIS Networking Event
(Location: Exhibition Area – Level 3)
8:00 AM – 9:30 AM Scientific Concurrent Sessions 1

Session 3:
Innovation in Craniofacial Tissue Engineering: Biomaterials Revolutionizing Regenerative
Dentistry and Medicine
Session Chair: Juan Taboas, Niloufar Abedi

8:00 AM – 8:30 AM Keynote Lecture: Regenerative Dentistry is here! Pamela C. Yelick
8:30 AM – 8:45 AM OP-11 Decellularization of Full-Thickness Facial Grafts Produces Preserved 3D Composite Biological Scaffolds With Patent Vascular Network, Antonio Menini, Italy
8:45 AM – 9:00 AM OP-12 T-Cells Drive Sexual Dimorphism in Experimental Periodontitis, Victoria Maglaras, US
9:00 AM – 9:15 AM OP-13 Endodontic Therapy of Immature Permanent Teeth With a Photocrosslinkable Hydrogel Versus Revascularization, Juan Taboas, US
9:15 AM – 9:30 AM OP-14 Interconnected Porous Architecture for Guided Bone Growth in Dental Implants, Rana Dabaja, US
9:30 AM – 10:00 AM Coffee Break
12:00 PM – 1:30 PM Lunch Break on Your Own
&
Empowering Next Leaders in TERM Luncheon (Greco Room) *registration required
1:30 PM – 3:00 PM Scientific Concurrent Sessions 2

Session 8:
The Next Frontiers: Emerging Applications of Biomaterials
Session Chairs: Marley Dewey, Aidan Gilchrist, Rana Ibrahim
1:30 PM – 2:00 PM Keynote Lecture: Biomaterials for NASA’s Missions, Lynn Rothschild
2:00 PM – 2:15 PM OP-27 Sacrificial Micropores Improve Diffusion Through an Immune-Isolating Capsule Containing a Human Ovarian Graft for Endocrine Function Without Compromising Immune Protection, Delaney Sinko, US
2:15 PM – 2:30 PM OP-28 An In Vitro Hydrogel-Based Model to Study Dormancy-Associated Drug Resistance in Metastatic Breast Cancer Spheroids, Shreyas Rao, US
2:30 PM – 2:45 PM OP-29 Investigating Coral Cell-Biomaterial Interactions to Drive Coral Reef Repair, Renata Dos Reis Marques, US
2:45 PM – 3:00 PM OP-30 Hydrogel-Supported Patient-Derived Tumor Explants for Drug Development, Eliza Li Shan Fong, Singapore
3:00 PM – 3:05 PM Transition Break
3:05 PM – 4:35 PM Scientific Concurrent Sessions 3

Session 13:
Key Variables Influencing VML Injury and Repair: Sex, Age, and Anatomical Location

Session Chairs: Sarah Greising, Jacob Quint, Eileen Su
3:05 PM – 3:35 PM Keynote Lecture: Sex, Drugs, and VML: Determinants of Muscle Bioenergetics and Redox Physiology, Jarrod Call
3:35 PM – 3:50 PM OP-45 Assessing Potential of Hyaluronic Acid-Based Hydrogels to Treat VML Injuries in Rat Lateral Gastrocnemius, George Christ, US
3:50 PM – 4:05 PM OP-46 The Role of Ovarian Hormones in Metabolic and Functional Recovery Following Volumetric Muscle Loss, Angela Bruzina, US
4:05 PM – 4:20 PM OP-47 Improving Regeneration of Traumatic Muscle Injuries Through a Primed Muscle Graft, Jacob Quint, US
4:20 PM – 4:35 PM OP-48 Apolipoprotein E3 Improves Motor Endplate Formation in Skeletal Muscle, Michael McClure, US
4:35 PM – 5:05 PM Coffee Break
5:05 PM – 6:35 PM Scientific Concurrent Sessions 4

Session 18:
Bioimaging and Sensing for Cell Tracking, Scaffold Validation, and Organ Preservation

Session Chair: Mrignayani Kotecha
5:05 PM – 5:35 PM Keynote Lecture: Coloring the Future of Cell Tracking, Bryan Smith
5:35 PM – 5:50 PM OP-61 Engineering Photon Upconverting Oxygen Nanosensors for Noninvasive In Vivo Monitoring of Implanted Cell Therapies, John-Paul Pham, US
5:50 PM – 6:05 PM OP-62 AI-Assisted Metabolic Optical Biomarkers for Tracking Hematopoietic Stem/Progenitor Cells, Keyue Shen, US
6:05 PM – 6:20 PM OP-63 Development of Hardware and Protocols for Ex-Vivo Rat Liver Oxygen Imaging, Mrignayani Kotecha, US
6:20 PM – 6:35 PM OP-64 Multicolor Computed Tomography of 3D Printed Radiopaque Biomaterial Implants, Erik Shapiro, US
6:35 PM – 8:00 PM Poster Session 2 & Exhibitor Viewing / Reception
(Location: Exhibition Area – Level 3)
8:00 PM – 9:00 PM SYIS Networking Event
(Location: Exhibition Area – Level 3)
8:00 AM – 9:30 AM Scientific Concurrent Sessions 1

Session 4:
Osteoarthritis and Post-Traumatic Osteoarthritis: From Inflammation and Degeneration to Regenerative Therapies and Disease Diagnosis

Session Chair: Melanie Hart, Bernd Rolauffs, Amy Xie
8:00 AM – 8:30 AM Keynote Lecture: Single-Cell Morphological Profiling for Predicting Function as Diagnostics in Osteoarthritis (OA) and Post-Traumatic Osteoarthritis (PTOA), Bernd Rolauffs
8:30 AM – 8:45 AM OP-15 An Inflammatory Joint-on-a-Chip for Cartilage and Synovial Disease Modelling of Osteoarthritis, Brendan Lobo, Canada
8:45 AM – 9:00 AM OP-16 Characterization of Unreported Mass of Collagen Crosslinks Allows for Direct Detection of Lysyl Oxidase Derived Crosslinks in Serum, Ben Sexton, US
9:00 AM – 9:15 AM OP-17 Matrix-Bound Nanovesicles From Human Joint Tissues: Identifying Potential Biomarkers for Chronic Degenerative Joint Diseases, Catalina Pineda Molina, US
9:15 AM – 9:30 AM OP-18 Single-Cell Profiling Reveals Cytokine-Specific Modulation of Early Injury Responses in a Post-Traumatic Osteoarthritis Cartilage Model, Johannes Tenholt, Germany
9:30 AM – 10:00 AM Coffee Break
12:00 PM – 1:30 PM Lunch Break on Your Own
&
Empowering Next Leaders in TERM Luncheon (Greco Room) *registration required
1:30 PM – 3:00 PM Scientific Concurrent Sessions 2

Session 9:
Advances in Skin Tissue Engineering

Session Chairs: Erbil Abaci, Helena Zomer, Thanusha AV
1:30 PM – 2:00 PM Keynote Lecture: Capturing Cellular Dynamics During Wound Repair in Live Mice, Sangbum Park
2:00 PM – 2:15 PM OP-31 A Skin-on-a-Chip Model With a Continuous Tissue Geometry Captures the Mechanosignaling in Skin Fibrosis, Alberto Pappalardo, US
2:15 PM – 2:30 PM OP-32 Engineering 3D iPSC-Derived Skin Tissues for RDEB Disease Modeling Using an Optimized Skin Organoid Differentiation Method, Laura Garriga-Cerda, US
2:30 PM – 2:45 PM OP-33 OP-33 Cutaneous Squamous Cell Carcinoma in Patients With Epidermolysis Bullosa: A Novel Approach to Wound Closure Using a Decellularized Bovine Pericardium Scaffold, Yevheniia Fedorets, Ukraine
2:45 PM – 3:00 PM OP-34 OP-34 Efficient Methods For Engineering Autologous, Full-thickness Skin Grafts, Vaughan Feisst, New Zealand
3:00 PM – 3:05 PM Transition Break
3:05 PM – 4:35 PM Scientific Concurrent Sessions 3

Session 14:
Cardiac & Vascular Tissue Engineering

Session Chairs: Ying Wang, Feng Zhao, Tracey Moyston
3:05 PM – 3:35 PM Keynote Lecture: Harnessing Neutrophils for Vascular Graft Success: From Inflammation to Regeneration, Gary Bowlin
3:35 PM – 3:50 PM OP-49 Functional Heterogeneity of Endothelial Cells in Self-Assembled Engineered Vasculature, Bruno De Medeiros Esmeraldo, US
3:50 PM – 4:05 PM OP-50 Microfabricated Anisotropic Cardiac Microbundles For The Modular Assembly of Cardiac Tissue Grafts, Maggie Jewett, US
4:05 PM – 4:20 PM OP-51 In Vitro Construction of Human Blood Vessels From Vascular Decellularized Extracellular Matrix Endothelized With Human Adipose-Derived Mesenchymal Stromal Cells, Sara Febbraio, Italy
4:20 PM – 4:35 PM OP-52 OP-52 Cardiac Extracellular-Derived Matrikine for Cardiac Regeneration Following Myocardial Infarction, Yan-Ru Lai, US
4:35 PM – 5:05 PM Coffee Break
5:05 PM – 6:35 PM Scientific Concurrent Sessions 4

Session 19
Harnessing Responsive Biomaterials for Next-Generation Therapeutics

Session Chair: Brendon Baker, Claudia Loebel
5:05 PM – 5:35 PM Keynote Lecture: Mechano-Regulated Therapeutic Delivery for Joint Injury and Repair, Robert Mauck
5:35 PM – 5:50 PM OP-65 Genetically Programmed Superparamagnetic Soft Robots for Microsurgery, Wenwen Huang, China
5:50 PM – 6:05 PM OP-66 A CRISPR-Engineered Isogenic 3D Bioprinted Outer Blood-Retinal Barrier Model to Investigate the Role of CFH in AMD, Andrea Barabino, US
6:05 PM – 6:20 PM OP-67 Engineered Silk Elastin-Like Protein Nanoparticles With Calcium Phosphate Coating Enable Safe and Effective Antitumor Chemotherapy, Kaiyue Zhang, China
6:20 PM – 6:35 PM OP-68 Programmed Sequential Release of Growth Factors Using Janus Acoustically Responsive Scaffolds for Vascular Regeneration, Haijun Xiao, US
6:35 PM – 8:00 PM Poster Session 2 & Exhibitor Viewing / Reception
(Location: Exhibition Area – Level 3)
8:00 PM – 9:00 PM SYIS Networking Event
(Location: Exhibition Area – Level 3)
7:00 AM – 8:00 AM TWIGs Chairs Meeting (Location: Michelangelo Room)
8:00 AM – 9:30 AM Scientific Concurrent Sessions 1

Session 5:
Rapid Fire I

Session Chair: Evelyn Yim
8:00 AM – 8:05 AM RF-01 Matrix Mechanics And HA Composition Regulate NK Cell Infiltration In Engineered Hydrogels, Suzanne Lightsey
8:05 AM – 8:10 AM RF-02 Chaotic Printing Of Microvasculature For Bone Tissue Engineering: Micro-channeled Hydrogel Sheets, David Dean
8:10 AM – 8:15 AM RF-03 Design And Optimization Of A Cost-effective Normothermic Ex Vivo Kidney Perfusion System: A Novel Approach Eliminating Rbcs And External Oxygen Supply, Chun Tat Lui
8:15 AM – 8:20 AM RF-04 Melt Electrowriting And Fused Deposition Modeling 5-axis Printing Of Personalized Corneal Scaffolds, Javier Vazquez-Armendariz
8:20 AM – 8:25 AM RF-05 Development Of A Sensor Integrated Bladder Bioreactor System For Reconstructive Procedures, Brendyn Miller
8:25 AM – 8:30 AM RF-06 A Biomimetic Bone-like Organoid Platform As A Model For Skeletal Tissue Engineering, Genevieve Romanowicz
8:30 AM – 8:35 AM RF-07 Repairing Volumetric Muscle Loss With Tissue-engineered Skeletal Muscle Units In The Ovine Peroneus Tertius Muscle Model, Eileen Su
8:35 AM – 8:40 AM RF-08 Erythroid Progenitor Activation Modulates Oxygen Tension And Enhances Bone Regeneration Following Fracture, Annemarie Lang
8:40 AM – 8:45 AM RF-09 Understanding Mechanical Dysregulation Of Tendon Development To Inform Regeneration Strategies, Catherine Kuo
8:45 AM – 8:50 AM RF-10 Oxygen-dependent Regulation Of Tendon Extracellular Matrix, Stephanie Steltzer
8:50 AM – 8:55 AM RF-11 Extracellular Matrix Hydrogel Reduces Fibrosis In A Canine Model Of Volumetric Muscle Loss, Shanae Butler
8:55 AM – 9:00 AM RF-12 An Automated High Throughput 3d Engineered Heart Tissue Platform For Disease Modeling And Drug Discovery, Daniel Sauter
9:00 AM – 9:05 AM RF-13 Light-Based 3D Printing Of Oxygen-generating Nanocomposite Scaffolds Accelerates Bone Regeneration, Anastasia B Timoshenko
9:05 AM – 9:10 AM RF-14 Impact Of Biomanufacturing Process On Functional Outcomes Following Implantation Of A Human Tissue Engineered Muscle Repair (TEMR) Construct In A Tibialis Anterior (TA) Volumetric Muscle Loss (VML) Model in Athymic Rats, Kira Bourret
9:10 AM – 9:15 AM RF-15 Investigation Into The Specific Inflammatory Contributors Of Bioprosthetic Heart Valve Mineralization In A Subdermal Immunodeficient Mouse Model, Chima Ofoegbu
9:15 AM – 9:20 AM RF-16 Detailed Study Of The Etiology Of Graft Stenosis In Tissue Engineered Vascular Graft In A Porcine Model, Yuta Tsuchida
9:20 AM – 9:25 AM RF-17 Clickable PEGNB Microgels Support Bioprinting And Microvascular Assembly Towards Hierarchical Vascular Applications, Irene Zhang
9:25 AM – 9:30 AM RF-18 4D Bioprinting of Magnet-integrated Tissue Construct to Mimic Hierarchical Architecture of Left Ventricle, Hwanyong Choi
9:30 AM – 10:00 AM Coffee Break
12:00 PM – 1:30 PM Lunch Break on Your Own
&
Empowering Next Leaders in TERM Luncheon(Greco Room) *registration required
1:30 PM – 3:00 PM Scientific Concurrent Sessions 2

Session 10:
Revitalizing Tissues: Harnessing Extracellular Vesicles & Mitochondria

Session Chairs: Golnaz Karoubi
1:30 PM – 1:50 PM OP-35 Transport of Mature MicroRNA Into Mesenchymal Stem Cell Extracellular Vesicles, Niloufar Abedi, US
OP-36 Placental Mesenchymal Stem Cell-Derived Extracellular Vesicles Alleviate Liver Fibrosis by Inactivating Hepatic Stellate Cells, Weixin Zhao, US
1:50 PM – 2:10 PM OP-37 Micropuncture Enhances Endothelial Cell Release of Pro-Angiogenic Exosomes, Jazzmyn Dawes, US
2:10 PM – 2:30 PM OP-38 Analytical Comparison of MSC-EV Quality Attributes Across Tissue Sources and Production Platforms, Elie Zakhem, US
2:30 PM – 2:45 PM OP-39 Mitochondrial Transplantation to Attenuate Endothelial Dysfunction in Diabetes Mellitus, Natalia Matiuto, US
2:45 PM – 3:00 PM OP-40 Comparative Effects of Hypoxic vs. Normoxic Mesenchymal Stem Cell-Derived Extracellular Vesicles on Muscle Regeneration Following Volumetric Muscle Loss (VML), Avantika Jain, US
3:00 PM – 3:05 PM Coffee Break
3:05 PM – 4:35 PM Scientific Concurrent Sessions 3

Session 15:
Tissue Engineering Models of the Nervous System

Session Chairs: Nisha Iyer, Jessica Butts, Manini Bhatt
3:05 PM – 3:35 PM Keynote Lecture: Designing Microphysiological Systems to Evaluate Neural Interfaces and Interactions, Christina M Tringides
3:35 PM – 3:50 PM OP-53 A Three-Dimensional iPSC-Derived Midbrain Neuron Culture for Modeling Opioid Addiction, Ze Zhong Wang, US
3:50 PM – 4:05 PM OP-54 Mesoscale Neuromuscular Model for Mapping and Modulating Independent Motor Units, Angel Bu, US
4:05 PM – 4:20 PM OP-55 Determining the Role of Notch Signaling in Atoh1 Hindbrain Lineage Cell Fate Decisions, Madison McLaren, US
4:20 PM – 4:35 PM OP-56 Contactless Acoustic Patterning for Neural Tube and Vessel Development, Weiping Li, US
4:35 PM – 5:05 PM Coffee Break
5:05 PM – 6:35 PM Scientific Concurrent Sessions 4

Session 20:
Rapid Fire II

Session Chair: George S Hussey
5:05 PM – 5:10 PM RF-19 Ecm-inspired Immunomodulatory Il-37 for Improving Outcomes of Implanted Mesh in Aged Individuals, Bryan Brown
5:10 PM – 5:15 PM RF-20 Enhancing the Migration and Differentiation of Mesenchymal Stromal Cells in Composite Collagen Hydrogels Using Focused Ultrasound, Somnath Maji
5:15 PM – 5:20 PM RF-21 A Bioengineered Dermal-inspired Interwoven Extracellular Matrix Wound Patch Recapitulating Nativity for Promoting Diabetic Wound Healing, Feng Zhao
5:20 PM – 5:25 PM RF-22 Self-expanding Silogel Sponges with Antimicrobial and Hemostatic Functionality, Pritha Sarkar
5:25 PM – 5:30 PM RF-23 Defining the Role of Matrix-bound Nanovesicles in Modulating Epithelial and Mesenchymal Cells in the Tumor Microenvironment Remodeling, Daniela Romero
5:30 PM – 5:35 PM RF-24 Alleviation of Oxidative Stress in Fibroblasts by Platinum Nanoparticle-immobilised Polycaprolactone-collagen Nanofibres, Matangi P R
5:35 PM – 5:40 PM RF-25 From Plants to Healing: Incorporating Aloe Vera-derived Nanoparticles into Soy Protein Biomatrices for Enhanced Wound Healing, Nader Rezazadeh
5:40 PM – 5:45 PM RF-26 Modular Fibrous Architecture Designed to Promote Integrin-VEGFR Crosstalk Enhances the Vascularization of Synthetic Nanoporous Hydrogels, Yimeng Zhao
5:45 PM – 5:50 PM RF-27 Role of Estrogen Signaling in Skin Aging and Repair, Helena Zomer
5:50 PM – 5:55 PM RF-28 Engineering Tolerogenic Cell Therapies with Placental Mimicry for Type 1 Diabetes, Shivani Hiremath
5:55 PM – 6:00 PM RF-29 Modeling Immune-ECM Crosstalk and Therapeutic Response in an Aged Breast Cancer Model, Lauren Hawthorne
6:00 PM – 6:05 PM RF-30 Antigen-conjugated Scaffolds for Enrichment of Disease-specific T-cells, Sydney Wheeler
6:05 PM – 6:10 PM RF-31 Damp-scavenging Scaffolds for Immunomodulation in an In Vitro Model of Osteoarthritis, Brianna Pryzwozny
6:10 PM – 6:15 PM RF-32 Creating a Living Intestinal Organoid Biobank: A Model System for Mechanistic Testing in GI-symptomatic Children with Autism, Yosauri Fernandez Figuereo
6:15 PM – 6:20 PM RF-33 Improving the Efficiency of Red Blood Cell Manufacturing, Shannon Walen
6:20 PM – 6:25 PM RF-34 Targeting Ph-regulatory Mechanisms in Nucleus Pulposus Cells to Overcome the Acidic Barrier for Disc Regeneration, Tynhinane Hamidouche
6:25 PM – 6:30 PM RF-35 Morphometric Profiling of Mesenchymal Stem Cells as a Predictive Tool for Regenerative Medicine, Emine Berfu Ozmen
6:30 PM – 6:35 PM RF-36 Customized Hyaluronan-based Hydrogel as a Carrier Material for Retinal Pigment Epithelium (RPE) Cell Transplantation, Laura Yla-Outinen
6:35 PM – 8:00 PM Poster Session 2 & Exhibitor Viewing / Reception
(Location: Exhibition Area – Level 3)
8:00 PM – 9:00 PM SYIS Networking Event
(Location: Exhibition Area – Level 3)
8:00 AM – 9:30 AM Scientific Concurrent Sessions 5

Session 21:
Emerging Biofabrication Technologies

Session Chair: Feng Guo
8:00 AM – 8:30 AM Keynote Lecture: Neural organoids on chip towards learning and memory modeling, Lena Smirnova
8:30 AM – 8:45 AM OP-69 Matrix-Free Fabrication of Reproducible and Functional Human Intestinal Organoids With Control of Polarity, Madeline Eiken, US
8:45 AM – 9:00 AM OP-70 A Multiscale Bioprinting Platform for the Fabrication of Hierarchically Aligned Cardiac Tissues, Donghwan Kim, Korea
9:00 AM – 9:15 AM OP-71 Embedded Bioprinting of Airway and Alveolar Stem Cells Enables Guided Morphogenesis of Complex 3D Lung Tissues, Barbie Varghese, US
9:15 AM – 9:30 AM OP-72 Matrix Mechanics Modulates the Permeability and Contractility of Endothelium Within Engineered Microvessels, Margaret Stanley, US
9:30 AM – 10:00 AM Coffee Break
10:00 AM – 12:00 AM

Plenary Speaker & Award Session 2

Using Organoids to Interrogate Human Development and Cellular Heterogeneity, Jason Spence

2025 TERMIS-AM Lifetime Achievement Award
Nicholas Peppas

12:00 PM – 1:30 PM Lunch Break on Your Own
&
SYIS Student Meet Mentor Lunch (Greco Room) *registration required
1:30 PM – 3:00 PM Scientific Concurrent Sessions 6

Session 26:
Engineered Microenvironmental Cues for Musculoskeletal Regeneration

Session Chairs: Annemarie Lang, Genevieve Romanowicz, Emine Berfu Ozmen
1:30 PM – 2:00 PM Keynote Lecture: Biomaterial-Guided Tendon Regeneration, Brendon M. Baker
2:00 PM – 2:15 PM OP-85 Identification of MRTF as a Key Regulator of Tendon Mechanobiology During Embryonic Development, Emily King, US
2:15 PM – 2:30 PM OP-86 Microfiber-Reinforced Hydrogel Constructs Promote High-Precision Cellular Alignment, Mechanical Stability and Myogenic Differentiation, Adam Rauff, US
2:30 PM – 2:45 PM OP-87 Osmotic Niche Changes Tune Extracellular Matrix Viscoelasticity and Trigger Bone Regenerative Processes, Matthias Kollert, Germany
2:45 PM – 3:00 PM OP-88 Mechanostat-on-a-Chip: Investigating Mechanotransduction by Utilizing Microphysiological Systems and Organoids, Frank Schulze, Germany
3:00 PM – 4:45 PM

2025 TERMIS-AM Awards

Senior Scientist Award
Joyce Y. Wong

Commercialization/Innovation Award
Jeff Karp

Young Investigator Award
Awardee Presentation: Determining Sex Differences in Cardiovascular Diseases Using Engineered Tissues, Brian Aguado

Outstanding Postdoc Award
Gopal Agarwal

WFIRM Young Investigator Travel Awards
4:45 PM – 5:15 PM TWIGs Organizational Meetings
5:15 PM – 6:45 PM Poster Session 3 & Exhibitor Viewing / Reception
(Location: Exhibition Area – Level 3)
6:45 PM – 7:00 PM Transition break
7:00 PM – 9:00 PM 7:00 PM – 9:00 PM
Evening Special Event – Conference Reception
8:15 PM – 8:30 PM
SYIS Career Development and Scientific Excellence Award Presentation
(Location: Level 4)
8:00 AM – 9:30 AM Scientific Concurrent Sessions 5

Session 22:
Engineering Strategies to Aid in Diagnosis and Treatment of Ophthalmic Disease

Session Chairs: Budd A Tucker, Ruchi Sharma
8:00 AM – 8:25 AM Keynote Lecture: Engineering Next Generation Microphysiologic Systems for the Study and Treatment of Diabetic Retinopathy, Maribel Vasquez
8:25 AM – 8:50 AM Keynote Lecture: Evaluating and Engineering a Self-Amplifying RNA System for Gene Therapy, Michael Farkas
8:50 AM – 9:00 AM RF-39 Sustained Release Of Insulin-like Growth Factor 1 For The Treatment Of Retinal Degenerative Diseases, Sophia Lu, US
9:00 AM – 9:10 AM OP-74 Non-Destructive Assessment of Retinal Organoid Maturity for Consistent Photoreceptor Replacement Therapies, Nicholas Stone, US
9:10 AM – 9:20 AM OP-75 In Vitro Quality Screening of Human Corneal Stromal Stem Cells for Cell-Based Therapy of Corneal Scarring, Gary Yam, US
9:20 AM – 9:30 AM OP-76 Role of Substrate Biomechanical Properties in Epigenetic Modulation and Phenotypic Stability of Corneal Endothelial Cells, Saad Asim, US
9:30 AM – 10:00 AM Coffee Break
12:00 PM – 1:30 PM Lunch Break on Your Own
&
SYIS Student Meet Mentor Lunch (Greco Room) *registration required
1:30 PM – 3:00 PM Scientific Concurrent Sessions 6

Session 27:
Rapid Fire III

Chair: Peter Ma
1:30 PM – 1:35 PM RF-37 Topographical Immunoregulation to Enhance Osteogenesis Under Diabetic Conditions In-Vivo, Min Guk Kim
1:35 PM – 1:40 PM RF-38 Advancements in Surface Modification and Bioactive Coatings For Organ-on-Chip Technologies, Carolina Centeno-Cerdas
1:40 PM – 1:45 PM RF-39/1 Efficient Engineering of Nonliving Mesenchymal Stem Cells for Innovative Cellular Therapies, Tiep Nguyen
1:45 PM – 1:50 PM RF-40 Matrix-bound Nanovesicles: A Novel Paradigm for Cartilage Preservation in Osteoarthritis Through Tissue Engineering Insights, Jiayang Rong
1:50 PM – 1:55 PM RF-41 Improving Mechanical Properties and Printability of Collagen Hydrogels through UVA-Riboflavin Crosslinking and Silk Fibroin Incorporation, Vipuil Kishore
1:55 PM – 2:00 PM RF-42 Machine Learning-based Early Prediction of Type 1 Diabetes from Immunological Niche Gene Signatures, Yifei Jiang
2:00 PM – 2:05 PM RF-43 Liver Extracellular Matrix Exposure Induces Dormancy Signatures in Colorectal Cancer Spheroids, Lucia Nash
2:05 PM – 2:10 PM RF-44 Engineering a Novel Synergistic Nanoscaffold Incorporating Green Tea and Acacia Catechu Extracts for Accelerated Healing of Diabetic Foot Ulcers, Vivek Radhakrishnan
2:10 PM – 2:15 PM RF-45 Deciphering Avascular Tissue Regeneration in The Human Knee Meniscus via In Vitro Models, John Bradford
2:15 PM – 2:20 PM RF-46 Antibacterial and Immunomodulatory Colloidal Scaffolds for the Treatment of Burns: Recombinant Human Proteoglycan (PRG4) and Minocycline in Gelatin Methacryloyl (GELMA) Foam, Tannin Schmidt
2:25 PM – 2:30 PM RF-48 Reconstructing the Uterine Microenvironment Using a Tunable 3D Hydrogel Platform for Investigation of Early Embryonic Morphogenesis in Pigs, Angie Pannier
2:30 PM – 2:35 PM RF-49 Fibrous Hydrogels Facilitate Matrix Remodeling in the Culture of Human Ovarian Stromal Cells, Taylor Schissel
2:35 PM – 2:40 PM RF-50 Non-Destructively Assessing Microcarrier Occupancy Using Average Acoustic Pulse Dispersion Length, Jean Welter
2:40 PM – 2:45 PM RF-51 Multi-material 3D Bioprinting of Human Stem Cells to Engineer Complex Human Corneal Structures with Stroma and Epithelium, Paula Puistola
2:45 PM – 2:50 PM RF-52 Optimizing Ring Frequency in Esophageal Grafts: Finite Element Analysis for Enhanced Structural Support and Stability, Federica Cosentino
2:50 PM – 2:55 PM RF-53 Integration of an Innovative, Non-invasive, Long-lived, Robust Optical O2 Sensor into an Automated Manufacturing System, Mike Jacobs
2:55 PM – 3:00 PM RF-54 Integration of Oxygen Sensors Within 3D Biomimetic Scaffolds for Tissue Regeneration, Jean Welter
5:15 PM – 6:45 PM Poster Session 3 & Exhibitor Viewing / Reception
(Location: Exhibition Area – Level 3)
6:45 PM – 7:00 PM Transition break
7:00 PM – 9:00 PM 7:00 PM – 9:00 PM
Evening Special Event – Conference Reception
8:15 PM – 8:30 PM
SYIS Career Development and Scientific Excellence Award Presentation (Location: Level 4)
8:00 AM – 9:30 AM Scientific Concurrent Sessions 5

Session 23:
Role of Biomaterials, Biomolecules and Processes in Musculoskeletal Tissue Regeneration

Session Chairs: Karina Nakayama, Cevat Erisken, Kayla Podlewski
8:00 AM – 8:25 AM Keynote Lecture: Engineering the Regenerative Niche for Multi-Tissue Musculoskeletal Repair, Nick Willett
8:50 AM – 9:00 AM OP-77 Enhancing Effective Fracture Healing in Ageing Bone: Bioengineered Extracellular Vesicles as Osteochondrogenesis Activators for Targeted Therapy, Kelvin Yeung, Hong Kong
9:00 AM – 9:10 AM OP-78 Mechanical Compression and Shear Induce Distinct Macrophage Polarisation and Subsequent Mesenchymal Stromal Cell Differentiation, Martin Stoddart, Switzerland
9:10 AM – 9:20 AM OP-79 Synthetic Helical Peptides on Nanofibers 3D Scaffold to Activate Cell-Surface Receptors and Synergistically Enhance Critical-Sized Bone Defect Regeneration, Tongqing Zhou, US
9:20 AM – 9:30 AM OP-80 Advanced Bioprinting of Hydrogels With Controlled Mineral Gradients for Osteochondral Interface, Cevat Erisken, Kazakhstan
9:30 AM – 10:00 AM Coffee Break
12:00 PM – 1:30 PM Lunch Break on Your Own
&
SYIS Student Meet Mentor Lunch (Greco Room) *registration required
1:30 PM – 3:00 PM Scientific Concurrent Sessions 6

Session 28:
Immunomodulatory Engineering Platforms

Session Chairs: Brian Kwee, Robert Smitty Oakes, Tracey Moyston
1:30 PM – 2:00 PM Keynote Lecture: Local antigen specific B-cell recruitment improves regenerative healing in diabetic wounds, Tatiana Segura
2:00 PM – 2:15 PM OP-89 Integrating Immune Adjuvants Within Extracellular Matrix (ECM) Scaffolds to Modulate Host Response in Volumetric Muscle Loss Repair, Weizhen Li, US
2:15 PM – 2:30 PM OP-90 Glycan-Functionalized Biomaterial Reveals Early Immune Signatures of Type 1 Diabetes via Single-Cell Metabolic Profiling Using Flow Cytometry, Kayle Riley, US
2:30 PM – 2:45 PM OP-91 Amphiregulin Releasing Alginate Hydrogels for Treating Ischemic Muscle Injuries, Brennagh Shields, US
2:45 PM – 3:00 PM OP-92 Biomaterial Platforms for Monitoring and Treating Immune Dysfunction, Aaron Morris, US
5:15 PM – 6:45 PM Poster Session 3 & Exhibitor Viewing / Reception
(Location: Exhibition Area – Level 3)
6:45 PM – 7:00 PM Transition break
7:00 PM – 9:00 PM 7:00 PM – 9:00 PM
Evening Special Event – Conference Reception
8:15 PM – 8:30 PM
SYIS Career Development and Scientific Excellence Award Presentation (Location: Level 4)
8:00 AM – 9:30 AM Scientific Concurrent Sessions 5

Session 24: Special Topic:
The Importance of Advocacy in Biomedical Engineering Research

Session Chair: Dawn Beraud
8:00 AM – 8:30 AM Keynote Speaker: A Collective Call to Action: The Importance of Advocacy and Avenues for Engagement in Biomedical Engineering, Dawn Beraud
8:30 AM – 8:45 AM Keynote Speaker: Science for Everyone: Building Bridges Between the Lab and the Public, Elizabeth Cosgriff-Hernandez
8:45 AM – 9:00 AM Keynote Speaker: Building Relationships: Interfacing With Elected Officials From Local to National, Joyce Y. Wong
9:00 AM – 9:15 AM Keynote Speaker: Campus Perspectives on Biomedical Engineering Advocacy, Brendan A. Harley
9:15 AM – 9:30 AM Panel Discussion
9:30 AM – 10:00 AM Coffee Break
12:00 PM – 1:30 PM Lunch Break on Your Own
&
SYIS Student Meet Mentor Lunch (Greco Room) *registration required
1:30 PM – 3:00 PM Scientific Concurrent Sessions 6

Session 29:
Mechanobiological Microenvironments and Stimuli for Cell Programming/Reprogramming

Session Chair: Chia-Ching (Josh) Wu, Allen Liu, Sungmin Nam, Zhiyue Zhu
1:30 PM – 2:00 PM Keynote Lecture: Understanding & Re-Writing Cellular & Molecular Programs Within Skeletal Muscle, Carlos Andres Aguilar
2:00 PM – 2:15 PM OP-93 IPSC-Derived Tissues on Chips for Modeling Human Development and Disease, Estelle Park, US
2:15 PM – 2:30 PM OP-94 Smart Microfluidic Biochip With Real-Time Feedback for Enhancing Stem Cell Potential via Spheroid Compression, Chia-Ching (Josh) Wu, Taiwan
2:30 PM – 2:45 PM OP-95 Effects of Space Environment on Mesenchymal Stem Cells Immunosuppressive Potency, Leonel Velez Roman, US
2:45 PM – 3:00 PM OP-96 Transcriptional Landscape of Direct Reprogramming Toward Hematopoietic Stem Cells, Jillian Cwycyshyn, US
5:15 PM – 6:45 PM Poster Session 3 & Exhibitor Viewing / Reception
(Location: Exhibition Area – Level 3)
6:45 PM – 7:00 PM Transition break
7:00 PM – 9:00 PM 7:00 PM – 9:00 PM
Evening Special Event – Conference Reception
8:15 PM – 8:30 PM
SYIS Career Development and Scientific Excellence Award Presentation (Location: Level 4)
8:00 AM – 9:30 AM Scientific Concurrent Sessions 5

Session 25:
Dynamic Extracellular Matrices to Control Cell Signaling

Session Chair: Ritu Raman, Golnaz Karoubi, Diya Singhal
8:00 AM – 8:15 AM OP-81 Epithelial Cell Nascent Matrix Deposition Contributes to Lung Injury, Donia Ahmed, US
8:15 AM – 8:30 AM OP-82 Programmable Vascular Patterning via Actuating Extracellular Matrices, Jessica Shah, US
8:30 AM – 8:45 AM OP-83 Cyclic Stretch Preconditioning Improves Re-Epithelialization in Bioengineered Lung Scaffolds for Transplantation via Integrin-Mediated Mechano-Transduction, Golnaz Karoubi, Canada
8:45 AM – 9:00 AM OP-84 Probing Fibroblast Mechanobiology in Pelvic Organ Prolapse: An In Vitro Stiffness-Driven Model, Temitope Obisesan, US
9:00 AM – 9:30 AM Keynote Lecture: MAP Hydrogels Modulate Collagen Assembly and Fibrotic Responses, Tatiana Segura
9:30 AM – 10:00 AM Coffee Break
12:00 PM – 1:30 PM Lunch Break on Your Own
&
SYIS Student Meet Mentor Lunch (Greco Room) *registration required
1:30 PM – 3:00 PM Scientific Concurrent Sessions 6

Session 30:
Careers in the Regen Med Industry

Session Chair: Jan Stegemann
1:30 PM – 3:00 PM

Panelists:
Susan Drapeau,
Madeline Eiken,
Luai Huleihel,
Daniel Sauter

This session is targeted at trainees at all levels who are interested in working in the regenerative medicine industry. A panel of industry professionals will discuss their roles and how trainees can prepare themselves for these positions. The purpose is for the audience to understand the professional roles that are available for scientists and engineers in the regen med space, including as they progress through their careers.
5:15 PM – 6:45 PM Poster Session 3 & Exhibitor Viewing / Reception
(Location: Exhibition Area – Level 3)
6:45 PM – 7:00 PM Transition break
7:00 PM – 9:00 PM 7:00 PM – 9:00 PM
Evening Special Event – Conference Reception
8:15 PM – 8:30 PM
SYIS Career Development and Scientific Excellence Award Presentation (Location: Level 4)
8:00 AM – 9:30 AM Scientific Concurrent Sessions 7

Session 31:
Integrated Multicellular Living Systems for Biological Machinery Assembly
and Regenerative Therapies

Session Chair: Sungmin Nam
8:00 AM – 8:20 AM Keynote Lecture: Role of Fibrin in the Microphysiological System of Neuroinflammation at the Blood-Brain-Interface, Bumsoo Han
8:20 AM – 8:40 AM Keynote Lecture: Cell Contractile Force-Mediated Morphodynamic Tissue Engineering via 4D Printed Hydrogel Scaffolds, Aixiang Ding
8:40 AM – 9:00 AM Keynote Lecture: Tissue-Interfacing Biomedical Devices for Tissue Regeneration and Rehabilitation, Sungmin Nam
9:00 AM – 9:15 AM OP-97 Bioprinting-Assisted Tissue Assembly of Hierarchically Vascularized Liver Grafts, Daekeun Kim, Korea
9:15 AM – 9:30 AM OP-98 Precisely Controlled Spheroid Encapsulation for Modulating 3D Microgel Viscoelasticity and Regulating Tissue Construct Functionality, Sangmin Lee, US
9:30 AM – 10:00 AM Coffee Break
10:00 AM – 11:00 AM

Plenary Speaker Session 3

Translation: From Idea to Commercial Product, Laura Niklason
11:00 AM – 11:15 AM Closing Ceremony
11:15 AM – 11:30 AM Transition Break
11:30 AM – 1:00 PM Scientific Concurrent Sessions 8

Session 36:
General Session on Bioreactors & Organs-on-Chips

Session Chair: Julio Cesar Aleman Hernandez
11:30 AM – 11:45 AM OP-117 MicroHeart: A Highly Accurate Heart-on-a-Chip Platform Based on a Novel Light Bioprinted Cardiac Microtissue, Aadi Bhensdadia, US
11:45 AM – 12:00 PM OP-118 Investigation of Fontan-Associated Thrombosis and Fibrotic Remodeling in a Bioengineered Model of a Liver Sinusoid, Isabel Joyce, US
12:00 PM – 12:15 PM OP-119 In Vivo Validation of Manufactured Stem Cell-Derived Pancreatic Islets Using a Scaled, Automated, and Closed Approach, Tessa DesRochers, US
12:15 PM – 12:30 PM OP-120 Cellular Interactions Govern Tissue Patterning in Tooth Root Organoids, Fatima Syed, US
12:30 PM – 12:45 PM OP-121 Airway Organ Tissue Equivalent Platform for Modeling Chlorine Gas Toxicology and Medical Countermeasure Efficacy, Sean Murphy, US
12:45 PM – 1:00 PM OP-122 Macrophages Alter Metabolism of Engineered Cardiac Tissue in Infarct Conditions, Frank Ketchum, US
1:00 PM – 2:00 PM SYIS Career Panel Discussion
8:00 AM – 9:30 AM Scientific Concurrent Sessions 7

Session 32:
Trends in Disease Modeling and Treatments Using Biomaterials and Microfluidics

Session Chairs: Luiz Bertassoni, Rui L Reis
8:00 AM – 8:30 AM Keynote Lecture: New Tools to Design Complex 3D Cancer Models Using Microfluidics and Living Optical Fibers, Rui L Reis
8:30 AM – 8:45 AM OP-99 3D Pancreatic Niche for Tracking T Cell Recruitment and Killing of Antigen-Specific Islets, Cherie Stabler, US
8:45 AM – 9:00 AM OP-100 Modeling Dynamic Myeloid-Fibroblast Crosstalk in Pancreatic Cancer Within a Microfluidic Platform, Mariana Viso, US
9:00 AM – 9:15 AM OP-101 Engineered Injectable Scaffolds as Synthetic Niches for Minimally Invasive Surveillance of Metastatic Breast Cancer Progression, Kathryn Kang, US
9:15 AM – 9:30 AM OP-102 Modelling Pulmonary Hypertension with 3D-printed Vascular Scaffolds: A Platform for Mechanobiology and Personalized Therapy, Naghmeh Abbasi, US
9:30 AM – 10:00 AM Coffee Break
11:15 AM – 11:30 AM Transition Break
11:30 AM – 1:00 PM Scientific Concurrent Sessions 8

Session 37:
Engineering Reproductive Tissues

Session Chair: Jessica D. Weaver, Maria Coronel, Matangi PR
11:30 AM – 12:00 PM Keynote Lecture: Biomimetic Scaffolds for Modeling Female Reproductive Tissues, Michelle Oyen
12:00 PM – 12:15 PM OP-123 Tissue Engineered In Vitro Human Myometrium: A New Approach to Quantify Myometrial Contractility, Shreya Raghavan, US
12:15 PM – 12:30 PM OP-124 Microporous Annealed Particle Hydrogel Promotes Revascularization of Transplanted Human Ovarian Tissue and Restoration of Ovarian Endocrine Function, Despina Pavlidis, US
12:30 PM – 12:45 PM OP-125 Macrophage Polarization: Impact on Matrix Remodeling and Downstream Healing Outcomes, Marrisa Therriault, US
12:45 PM – 1:00 PM OP-126 Engineering ECM Sequestering Fibrous Hydrogels to Promote Ovarian Folliculogenesis and Investigate Follicle-ECM Interactions, Emily Thomas, US
8:00 AM – 9:30 AM Scientific Concurrent Sessions 7

Session 33: General Session on Stem Cells & Cell Therapies & Developmental Biology and Cell Signaling

Session Chair: Golnaz Karoubi, Jinal Mehta
8:00 AM – 8:15 AM OP-103 Hipsc-Derived Functional Salivary Gland Organoids, Laura Sherwood, US
8:15 AM – 8:30 AM OP-104 Fluid Assisted Transformation of Fallopian Tube Secretory Epithelial Cells, Raneem Ahmad, US
8:30 AM – 8:45 AM OP-105 Engineering Materials to Interrogate the Role of the Microenvironment on Cardiac Reprogramming, Atticus McCoy, US
8:45 AM – 9:00 AM OP-106 Targeting Unique Mechanical Vulnerabilities in Peristalsis-Associated Malignant Progression in KRAS G12C Mutant Colorectal Cancers, Astha Lamichhane, US
9:00 AM – 9:15 AM OP-107 Extracellular Matrix Hydrogel Promotes the Long-Term Growth and Function of Transplantable Human Thyroid Organoids Derived From Induced Pluripotent Stem Cells, Paula Marin-Munoz, US
9:15 AM – 9:30 AM OP-108 Optimizing an In Vitro Platform to Assess Patient Feasibility in Autologous Cartilage Repair: A Tissue Engineering Perspective, Amy Xie, Australia
9:30 AM – 10:00 AM Coffee Break
11:15 AM – 11:30 AM Transition Break
11:30 AM – 1:00 PM Scientific Concurrent Sessions 8

Session 38:
Strategies for Regeneration of the Nervous System

Session Chair: Nisha Iyer, Jessica Butts
11:30 AM – 12:00 PM Keynote Lecture: Glia Engineering for CNS Wound Repair, Timothy O’Shea
12:00 PM – 12:15 PM OP-127 Engineering a Stem Cell Spheroid-Derived 3D Decellularized Matrix With Post-Decellularization Growth Factor Customization as a Bioactive Material for Brain Repair, Chieh-Cheng Huang, Taiwan
12:15 PM – 12:30 PM OP-128 Evaluation of in Situ Assembled Granular Hydrogel Scaffolds for Neural Progenitor Cells Delivery in a Severe Spinal Cord Injury Model, YuChi Huang, US
12:30 PM – 12:45 PM OP-129 Prevention of Nerve Growth and Evoked Pain With a Nerve Cap Graft Device, Bryan Brown, US
12:45 PM – 1:00 PM OP-130 Injectable Hydrogel Derived From Decellularized Human Peripheral Nerve Attenuates Neuroinflammation in a Rodent Spinal Cord Injury Model, Gopal Agarwal, US
8:00 AM – 9:30 AM Scientific Concurrent Sessions 7

Session 34:
Cell Manufacturing for Regenerative Medicine

Session Chair: Camilo A Mora Navarro, Leonel Vélez

8:00 AM – 8:30 AM Keynote Lecture: Bench-to-Orbit Scalable MSC Manufacturing on Engineered Biointerfaces, Maribella Domenech
8:30 AM – 8:45 AM OP-109 Impact of Microgravity on Mesenchymal Stem Cell Growth and Stemness, Carolina Rivera-Crespo, US
8:45 AM – 9:00 AM OP-111 Batch Manufacturing of Hepatocyte-Laden Polyelectrolyte Microcapsules With Tunable Internal Environments Using an Optimized Electrospray Technique, Rafael Ramos, US
9:00 AM – 9:15 AM OP-112 3D Bioprinting Strategies for Engineering Cornea: A Clinician’s Perspective, Vineet Joshi, India
9:15 AM – 9:30 AM OP-110 A 2.5D Culture Platform Enhances the Maturity of Human Ipsc-derived Skeletal Muscle Cultures and Promotes Long-term Contractility, Tamara Rossy, US
9:30 AM – 10:00 AM Coffee Break
11:15 AM – 11:30 AM Transition Break
11:30 AM – 1:00 PM Scientific Concurrent Sessions 8

Session 39:
Mentorship Session: Navigating the Pre-Tenure Journey
11:30 AM – 1:00 PM

Panelists:
Laura De Laporte, Chair of Macromolecular Materials for Medicine at RWTH Aachen University
Tatiana Segura, Professor, BME Duke University
Catherine Kuo, Professor, BioE University of Maryland
Lisa Larkin, Professor, Molecular and Integrative Physiology University of Michigan
Shelly Sakiyama-Elbert, Professor and Vice Dean of Research and Graduate Education, School of Medicine, University of Washington
David Kohn, Professor, BME University of Michigan

This session is geared towards assistant professors and late-stage postdoctoral fellows. It will host a panel of established professors who will answer audience questions on key topics in navigating the pre-tenure phase of academia. After a broad discussion, panelists and others will break into groups for more small group discussions.
8:00 AM – 9:30 AM Scientific Concurrent Sessions 7

Session 35:
Biofabrication of Heterogeneous Scaffolds for Regenerative Medicine

Session Chairs: Liqun Ning, Vahid Serpooshan, Shivesh Anand
8:00 AM – 8:30 AM Keynote Lecture: Truly Omnidirectional 3D Printing, Mark Skylar-Scott
8:30 AM – 8:45 AM OP-114 Development of a Hydrogel-Based Scaffold With a Schwann Cell Density Gradient for Peripheral Nerve Regeneration, Kylie Schmitz, US
8:45 AM – 9:00 AM OP-115 Printing Mechanics Into Biology: Voxel-Resolved Encoding of Spatiotemporal Stiffness Directs Cell Fate and Migration, Maryam Tilton, US
9:00 AM – 9:15 AM OP-116 Bioprinting for Spatial Control of Cell Deposition in Engineered Tissues, India Dykes, US
9:15 AM – 9:30 AM OP-113 Multimodal Shape Morphing in 4D Biofabricated Hydrogels via Biaxial Crosslinking Gradients, Aixiang Ding, US
9:30 AM – 10:00 AM Coffee Break
11:15 AM – 11:30 AM Transition Break
11:30 AM – 1:00 PM Scientific Concurrent Sessions 8

Session 40:
Accelerating Breakthroughs by Leveraging Microgravity

Session Chairs: Pinar Mesci, Davide Marotta
11:30 AM – 12:00 PM Keynote Lecture: Biomanufacturing Beyond Earth: Disruption, Innovation, and the New Industrial Revolution, Pinar Mesci, Davide Morotta
12:00 PM – 12:15 PM OP-131 Cellular Behaviors of Biomanufactured Vascularized Liver Tissue Constructs in Microgravity, Timothy Dobroski, US
12:15 PM – 12:30 PM OP-132 Surface Tension Enables Induced Pluripotent Stem Cell Culture in Commercially Available Hardware During Spaceflight, Maedeh Mozneb, US
12:30 PM – 12:45 PM OP-133 Beyond Microgravity: Considering Other Mechanical Features of Organoids and Tissue Models in Space, Meenal Datta, US
12:45 PM – 1:00 PM OP-134 Predicting Chemotherapy Response in Space Using Tumor Organoids in Simulated Microgravity, Nadeem Wajih, US